In high-risk patient, papule and vesicular eruptions accompanied by mild fever may occur 14 to 30 days after vaccination. They tend to occur in about 20% of acute lymphatic leukemia patients. Herpes zoster may occur in high risk patients, however, its incidence and severity have not been more serious than observed in naturally infected patients.
Common adverse events are injection site complaints (pain/soreness, swelling and/or erythema, rash, pruritus, hematoma, induration, stiffness), fever > 102°F (39°C) oral, Varicella like rash (generalized or injection site).